Dopamine’s Serotonin Scan

Posted in generic for wellbutrin on November 7th, 2011 by Sharon – Be the first to comment

There are a lot of medications on the market that affect blood flow and metabolism in the brain. Sertraline (Zoloft), for example, affects serotonin and, to a lesser extent, dopamine and acetylcholine. The ability of your brain to maintain adequate levels of serotonin is contingent upon the speed of the reuptake cycle. The faster your brain processes your serotonin the more susceptible you’ll be to depression and anxiety. The mechanism by which Selective Serotonin Reuptake Inhibitors (SSRIs) work is through the inhibition of the reuptake cycle. This allows the brain’s serotonin to remain in the brain for a longer period of time, which the brain uses to affect mood and a few other things such as appetite and sex drive.

Fluoxetine (Prozac) is in the same family of drugs (SSRIs) but seems to have a greater dopaminergic effect. This could be from an inhibition of the reuptake of dopamine or norepinephrine but could also be its effect on receptors of serotonin subtypes that aren’t as pronounced with Sertraline. It’s almost a mystery why two drugs from the same class can affect a person so differently. As the science becomes more and more clear we will be able to objectively list the brain’s neurotransmitters and all the subtypes. Everyone knows of serotonin as being a relaxing, nourishing chemical but, depending on the serotonin subtype, this transmitter can actually do the opposite. I’ve known some people who had panic attacks and sleepless nights on Prozac but found relief with Paxil or Zoloft.

Drugs such as Wellbutrin affect the dopamine receptors–several subtypes exist here as well. Basically, norepinephrine and dopamine excite a person’s mood and creates similar effects as caffeine. For some people this complements their natural brain chemistry. For others, it can be profoundly uncomfortable and can even make a person more depressed than they were to begin with.

There are a couple of important things to remember in regards to taking an SSRI. It is easy to forget that the way a person feels is being altered by the medication and to forget that this can be changed. Suicidal thoughts are a side effect and should be considered in light of your medication and dosage. In addition, drinking alcohol on some of these drugs make the alcohol not as effective, which may bring the patient to drink way more than their bodies can handle and then deadly overdoses occur. Also, the day of or the day after drinking alcohol will make these drugs less effective and can make a person depressed.

If you want to learn more about SSRIs an excellent book is Listening to Prozac. It’s not one of those anti-drug books written by fanatics. The field of brain chemistry is getting more exciting as researchers discover new aspects about the mood centers of the brain and how we can improve people’s lives and defeat mental health problems. The book Change Your Brain, Change Your Life by Daniel G. Amen is a great explanation of the different parts of the brain related to mood and motivation.

Please visit www.bonshops.com

Samuel Bryant

Significant weight loss associated with Wellbutrin — nice side effect, any success stories out there?

Posted in wellbutrin weight loss on November 4th, 2011 by Sharon – 4 Comments

I’m considering asking my doctor to prescribe Wellbutrin for both my mood swings (which I believe are hormone and stress-induced) as well as weight loss. Frankly, I’m hoping it’s the thing that can finally keep me on-track with eating better, and less.

Anybody out there have a significant weight loss (I’m hoping for 70-80 lbs myself) while taking it?

I have been on it for about a month, and its for post traumatic stress disorder… it makes you not compulsivly eat.. thats my worst habit when i am stressed, I have lost about 25lbs so far… I hope it continues! good luck

WELLBUTRIN – THE F PLAN

Posted in wellbutrin weight loss on November 1st, 2011 by Sharon – 2 Comments

0 WELLBUTRIN   THE F PLANMore at http://fiddaman.blogspot.com

GlaxoSmithKline associate general counsel, Lauren Stevens, has been indicted with making false statements and obstructing a federal investigation into illegal marketing of the a ‘drug’ for weight loss.

The indictment, due, I believe, to press restrictions, did not mention the name of the drug Stevens was making false statements about. However, in an exclusive from the New York Times, we can now see that Stevens was duping the FDA regarding Glaxo’s multi – functional antidepressant, Wellbutrin.

Wellbutrin has been re-badged as Zyban, an apparent smoking cessation drug and now it appears to be crystal clear that Stevens was ‘bigging it up’ as some sort of dietary pill!

This from the NYT:

The indictment accuses the Glaxo official, Lauren C. Stevens of Durham, N.C., of lying to the Food and Drug Administration in 2003, by writing letters, as associate general counsel, denying that doctors speaking at company events had promoted Wellbutrin for uses not approved by the agency. Ms. Stevens “made false statements and withheld documents she recognized as incriminating,” including slides the F.D.A. had sought during its investigation, the indictment stated.

So, not only was Wellbutrin an antidepressant and a smoking cessation drug…Glaxo also wanted it to be a pill for weight loss!

I can just see the promotional ad for this particular product.

“Are you depressed about your weight and yellow stained teeth from smoking? – Ask your doctor for Wellbutrin, the Swiss Army knife of all drugs from GlaxoSmithKline.”

Mary Anne Rhyne, Glaxo’s spokesperson, said, “…the company was cooperating fully with a federal investigation into allegations of illegal sales and marketing of Wellbutrin. Last year, it set aside $400 million to resolve the case, which is still pending.”

Resolve the case?

You mean, throw money at it doncha Mary?

Honestly, this company are amazing, they think they can throw money in the direction of every single claim made against them. They are a walking, talking psychopath with no remorse whatsoever. When was the last time you ever heard any sort of apology from the likes of Mary Anne Rhyne? This is the same woman who said in 2005, “If ‘discontinuation reactions’ occur in patients stopping [Seroxat], the majority will experience symptoms that are mild to moderate in intensity, and are usually limited to two weeks.”

Rhyne is the Director US Media Relations at GlaxoSmithKline.

Be interesting to see what Glaxo CEO, Andrew Witty, has to say about recent events regarding his company.

September saw the European regulators finally pull Glaxo’s Avandia…something they should have done many years ago. This coming hot on the heels of the BBC expose of their drug. Maybe the regulators should have listened to the hardened advocates that were writing about Avandia many years ago, Evie Pringle being one such person.

October saw Glaxo plead guilty to a number of charges regarding the appalling state of their factory in Puerto Rico – a fine of $750 million and the customary slap on the wrists ensued.

November:

Sees GlaxoSmithKline denying that their once best selling antidepressant, Paxil [Seroxat in UK] had anything to do with Anna Blyth being born with a narrowing of the aorta leading from the heart.

Song featured in video is Karaoke version of ‘Rasputin’ by Boney M

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The Truth About New Quit Smoking Drugs

Posted in bupropion side effects on October 31st, 2011 by Sharon – 6 Comments

One of two life-long smokers suffer and die from ailments caused by smoking. So there is a continuous struggle to make people give up this bad habit, and increase their life expectancy with all the means modern medicine has available today. This is why pharmaceutical companies are making sustained efforts to come up with new quit smoking drugs that reduce or neutralize the withdrawal symptoms and accelerate post-quitting cravings.

Two of the most famous and well-reputed new quit smoking drugs are Chantix and Bupropion. Both are non-nicotine medicines, that require a certain period of treatment in order to be effective and which should be supported by professional counseling sessions. Before starting using new quit smoking drugs, it is best to have all your medical investigations made and to have the doctor analyze your record.

Chantix is a new quit smoking drug that comes in tablet form. Produced by Pfizer, this drug was conceived for pregnant women and teenagers under 18 who have to quit smoking. It is varenicline tartrate derived and it is considered to have a superior rating smoking cessation than Zyban. The usual Chantix treatment lasts for 12 weeks, but administration of this new quit smoking drug can be extended to a longer period depending on the case.

Bupropion is considered another revolutionizing new quit smoking drug that enjoys great result in nicotine addiction cessation. Initially Bupropion was made to combat depression, but studies and trials have proved that it helps smokers’ wishing to quit. It is as effective as nicotine-based drugs, but it also prevents gaining weight. The most common side effects associated with the use of this new quit smoking drug is dry mouth and sleeplessness.

Studies were conducted on large groups of smokers to test responsiveness and efficiency of this new quit smoking drug, and the results were compared to those obtained by administration of nicotine based drugs, placebo and shots. It resulted that treatment with Bupropion is superior to nicotine administered transdermally.

Smoking is a hard bad habit to break, it takes patience, strong will and motivation to ensure the effectiveness of new quit smoking drug therapies. This is the purpose of taking a quit smoking counseling course, because it offers the psychological support that you need to get rid of smoking and all its side effects. Just think that after quit smoking drug treatment, you will be over unpleasant breath smell, tiredness, low immunity, persistent cough and so on.

Jonathan Fraser
http://www.articlesbase.com/medicine-articles/the-truth-about-new-quit-smoking-drugs-123590.html

Side effects of Bupropion?

Posted in bupropion side effects on October 28th, 2011 by Sharon – 2 Comments

I was curious of the side effects of the anti-anxiety/depression drug called Bupropion. I dont get horny anymore and can barely get it up and I’m 18 years old and I dont know what is wrong. Please help.

That is not one of the side effects of Bupropion – in fact, some doctors prescribe it to help improve sexual function.

Bupropion is not an anti-anxiety medication. It can increase anxiety, and that is listed as a possible side effect of it.

Different side effects of Bupropion (generic) vs. Wellbutrin XL? (Thinking of switching to generic but scared)?

Posted in bupropion side effects on October 26th, 2011 by Sharon – 4 Comments

I have been taking wellbutrin xl for about a year and 7 months. I was on 150 mg for the first 12 months, then 300 mg for the last 7. (I love it; I feel like I couldn’t have imagined a medicine that would make me feel so normal. Just… normal, and consistent, not "high" and no longer experiencing manic lows.) I have always used name brand because I could afford it and because my Dr. recommended it, and am hesitant about generics. The reason I’m hesitant is because I was on Ortho Tri Cyclen Lo (birth control) for a year or so, but the $60 copay was getting costly, so I switched to the generic… I had the worst depression I’ve had in 2 years, I ate literally 4 times what I eat on a normal basis, and was a psychotic mess. I would get depressed and hopeless for no real reason, every single day, and cried at least twice a day during that time. Without even really knowing why.. I was still on the Wellbutrin during that time but I may as well have been off of it. I thought I was just crazy, but then I went online and read other people’s experiences with that specific birth control and learned that many other people had this bad reaction to the generic, and ended up switching back to name brand. Needless to say, I did.
Anyway, so my co-pay for the Wellbutrin is $60 a month, and recently my Dr. has put me on other medications too so I want to cut costs and am thinking of switching to the generic (Bupropion)… But after a year & 1/2 of satisfaction with the name brand, added with my terrible experience with the generic of the birth control medicine vs name brand, I’m really scared to switch and wondering what other people’s experiences have been?
I don’t want to read drug facts, because I’ve done significant research already, I really just want to hear what other people have experienced from the generic, or from the generic compared to name brand. I realize that I need to weigh the options between spending the extra $ and the value of my health, etc etc, I’m not looking for advice, I’m just looking for other people’s side effects because that can give me an idea of how bad it may or may not be.
Please help… I don’t want to go through another experience like I did with my previous generic, so I could use some feedback.
Thanks!

This is a question you should discuss with your doctor. I take paxil and when I switched to the generic I started having problems. My doctor told me that some generics do not absorb as well as the brand name. With me we just increased the dosage of the generic and now I am doing very well.

Talk to your doctor!

Anybody know about the side effects of the medication Wellbutrin?

Posted in side effects wellbutrin on October 24th, 2011 by Sharon – 2 Comments

I just got put of Wellbutrin for depression and I was wondering what the main side effects are? Does it cause weight gain or weight loss? Also how effective is the medication? How long does it take to work?

Hello,

I’m a Pharmacist and the major side effect of Wellbutrin is insomnia. This can be minimized by taking the drug only once a day in the morning (for the XL tablets) or if you’re using the twice a day pills, taking the second dose no later than 3pm.

Besides insomnia, Wellbutrin can cause: weight loss, dry mouth, nausea and increased sweating.

Generally, anti-depressants need at least 4 weeks to notice any beneficial effect.

Hope this helps.

does wellbutrin xl cause weight gain?

Posted in wellbutrin weight gain on October 21st, 2011 by Sharon – 14 Comments

Getting ready to start wellbutrin xl, 300 mg a day, and wondered if anyone has experienced weight gain with this med?

I actually lost weight with it. I felt better and had more energy so I did more stuff than lay on the couch.

Does Wellbutrin Cause Weight Gain?

Posted in wellbutrin weight gain on October 19th, 2011 by Sharon – 1 Comment

I know it can cause weight loss, but I was also wondering if it could also cause weight gain…since I always hear people saying ALL anti-depressants have the potential to.

I have never read about weight gain. I have heard all antidepressants do, too.

Common side effects:
Abdominal pain; constipation; decrease in appetite; dizziness; dryness of mouth; increased sweating; nausea or vomiting; trembling or shaking; trouble in sleeping; weight loss (unusual)

Edit: My first 2 sentences made no sense. I will restate it. I have never read about Wellbutrin causing weight gain. But I have hear that antidepressants cause weight gain. LOL! Perhaps others do, but it does not seem to be the problem with wellbutrin.

I am taking Wellbutrin and started lexapro. will the wellbutrin balance out weight gain of ssri(lexapro)?

Posted in wellbutrin weight gain on October 17th, 2011 by Sharon – 2 Comments

I have been taking wellbutrin for depression and my doc added lexapro for my ocd and anxiety. When I was on Paxil about 2 years ago, I gained like 30 pounds. I lost all of it when I started taking wellbutrin instead. Will the wellbutrin help offset the weight gain of lexapro

I did not experience any weight gain from lexapro. I have several friends who are also on it and haven’t gain any weight.